As group winners, both United and PSG will be away in the first-leg matches, which are due to be played in February and they will host the second-leg games in March.
Champions League last 16 games are provisionally scheduled to take place in February and March 2018.
The first legs will be contested on February 13/14/20/21 and the second legs will be played on March 6/7/13/14.
All seeded group winners will play away in the first legs before hosting the second legs at home.
CHAMPIONS LEAGUE LAST-16 IN FULL
|Match||Leg 1||Leg 2|
|Juventus vs Tottenham||Feb 13||Mar 7|
|Basel vs Manchester City||Feb 13||Mar 7|
|Porto vs Liverpool||Feb 14||Mar 6|
|Real Madrid vs PSG||Feb 14||Mar 6|
|Chelsea vs Barcelona||Feb 20||Mar 14|
|Bayern Munich vs Besiktas||Feb 20||Mar 14|
|Sevilla vs Manchester United||Feb 21||Mar 13|
|Shakhtar Donetsk vs Roma||Feb 21||Mar 13|
Tottenham take on Juventus in Turin and Basel host Manchester City in the first of the last-16 first-leg games on February 13, with the second legs scheduled for March 7.
On Valentine's Day, Porto host Liverpool and Real Madrid welcome PSG to the Bernabeu, with the second legs set for March 6.
The second batch of last-16 first-legs gets under way on February 20, with Chelsea taking on familiar foes Barca at Stamford Bridge, while Bayern host Besiktas in Munich. The second legs for those ties take place on March 14.