Though neither team is assured of automatic promotion to the Premier League, both sides are in strong positions heading into the final furlong of the campaign.
Despite just two wins from their last six games, leaders Wolves are 11 points clear of third-placed Fulham with six matches left to play.
Cardiff, meanwhile, saw their run of eight successive wins ended by Sheffield United on Monday, a result that leaves them six points behind Friday's visitors, albeit with a game in hand.
|Game||Cardiff City vs Wolves|
|Date||Friday, April 6|
|Time||19:45 BST / 14:45 ET|
TV Channel & Live Stream
In the United States (US), the game can be watched via ESPN or through the WatchESPN app.
|US TV channel||Online stream|
In the United Kingdom (UK), the game can be watched live on TV on Sky Sports Main Event and Sky Sports Football and it can be streamed live online using Sky Go.
|UK TV channel||Online stream|
|Sky Sports Main Event/Sky Sports Football||Sky Go|
Squads & Team News
|Position||Cardiff City players|
|Defenders||Peltier, Bennett, Morrison, Manga, Bamba, Halford, Connolly, Traore|
|Midfielders||Paterson, Gunnarsson, Grujic, K Harris, Pilkington, Damour, Bryson, J Ward, M Harris|
|Forwards||Mendez-Laing, Zohore, Hoilett, Madine, Wildschut, Meite, Guonongbe, Healey|
Despite coming off the bench to snatch a stoppage-time equaliser against Sheffield United, Anthony Pilkington may have to make do with a place on the bench again.
Club captain Sean Morrison is also likely to start despite a controversial video of him taunting Derby County players appeared online earlier this week.
Joe Ralls, Danny Ward and Jazz Richards are all long-term injury absentees.
Potential Cardiff City starting XI: Etheridge; Manga, Morrison, Bamba, Bennett; Paterson, Grujic, Gunnarsson; Mendez-Laing, Zohore, Hoilett.
|Defenders||Doherty, Batth, Coady, Hause, Bennett, Roderick, Ofosu-Ayeh, Douglas, Boly, Vinagre|
|Midfielders||Saiss, Neves, N'Diaye, Gibbs-White|
|Forwards||Costa, Jota, Cavaleiro, Afobe, Bonatini, Mir, Enobakhare|
Ruben Neves and Matt Doherty are both back in contention and likely to start having missed the draw with Hull City through suspension.
Carl Ikeme - who continues his fight against cancer - remains the only absentee from the first-team squad.
Potential Wolves starting XI: Ruddy; Bennett, Coady, Boly; Doherty, Neves, Saiss, Douglas; Costa, Jota, Cavaleiro.
Betting & Match Odds
Wolves are favourites according to dabblebet , who offer odds of 11/8 on the league leaders to win, while Cardiff are priced at 11/5. A draw is available at 21/10.
Anthony Pilkington's stoppage time equaliser ensured Cardiff City are the side with all the momentum in the race to probably join Wolves in securing automatic promotion to the Premier League.
Though Neil Warnock's side missed out on equalling their club record of nine straight wins at Sheffield United on Monday, their form in the second half of the season means that a win on Friday could even make them the favourites to win the title.
Many are making the Bluebirds favourites to beat Wolves despite Nuno Espirito Santo's side sitting atop of the table for the majority of the campaign.
They have struggled for consistency in 2018, but a win in the Welsh capital would put them one win away from the Premier League and a maximum of three away from sealing the deal as title-winners.