Milan still have a mountain to climb if they want to reach their ambitions of playing in European football next season. A win would put the club at ninth at 51 points - four points back from Lazio in the Conference League slot and six points adrift from fourth-placed Bologna.
Milan need to finish fourth or above to secure Champions League qualification.
Pulisic continues to be the club's best attacker this season, with nine goals and eight assists in Serie A and an additional four goals and an assist in Champions League play. His other assist came in Coppa Italia.