The Arsenal friendly was just Yoro's second game for United following his big-money move from Lille. The Frenchman had to be withdrawn from the match in Los Angeles - which the Red Devils lost 2-1 - in what is a setback for Erik ten Hag given Yoro looked set to be an immediate starter.
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It's a case of deja vu for United and their supporters after last season's pre-season tour of the US was marred by injuries to Kobbie Mainoo and Amad Diallo. Not only is Yoro out with a significant injury, but striker Rasmus Hojlund also left the Arsenal game in the first half with an apparent hamstring problem.
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Yoro's injury may intensify United's efforts to sign another centre-back in the summer transfer window. They've been linked with a move for Bayern Munich's Matthijs de Ligt, and had two bids for Jarrad Branthwaite rejected by Everton. With Yoro now set to miss the Community Shield against Manchester City on August 10, and potentially Premier League games against Liverpool (September 1) and Tottenham (September 29), it wouldn't be a surprise if a new addition to the backline wasn't made a priority.