Ghana made a trip to Spain on Sunday for an international friendly game against Nicaragua at Francisco Artes Carrasco on Tuesday.
The Black Stars fell 3-0 against the South America heavyweights Brazil in another friendly played on Friday in France.
Coach Otto Addo is expected to play with three centre-backs against Nicaragua owing to players at his disposal.
Mohammed Salisu, Tariq Lamptey and Inaki Williams - who switched their allegiance recently, might make their full debuts as well.
GOAL predicts how the Black Stars might start.