Pablo De Blasis, Alexandru Maxim and Bote Baku efforts handed Sandro Schwarz’s men a comprehensive victory in the encounter.
And the loss could affect their aim for a Champions League spot after the defeat saw them drop to the sixth spot, five points adrift of fourth-placed Hoffenheim, and with two games left before the end of the season.
“You know, it's difficult to lose 3-0. We're all down. All I can say is that we're going to bounce back from this,” Lookman told Bundesliga website.
“It makes qualifying for the Champions League even more difficult. But you know, anything can happen in football. We just keep going."
Lookman has scored two goals in nine league appearances since he joined the Red Bull Arena outfit in January.