Having won six and lost none of their last eight fixtures, the Azzurri are 23/20 (2.15) favourites to maintain their strong form with another victory at the Allianz Riviera.
However, Oscar Tabarez’s men ran out 1-0 winners when the sides last met in at the World Cup in 2014, and are on offer at 9/4 (3.25) to come out on top once again in this one.
Three of the six meetings between the sides have resulted in draws, and you can get odds of 11/5 (3.20) on them cancelling each other out once again on this occasion.
While Antonio Conte’s successful first season at Chelsea has only underlined what a difficult man he was to follow at the helm of the national team, Gian Piero Ventura is so far making it look easy.
Despite kicking off with a 3-1 friendly defeat against a strong France team, the former Torino boss has seen his side fail to beat only Spain and Germany in the eight games since – with both of those matches ending in creditable draws.
Having overseen 22 goals scored and just four conceded in the remaining six victories, Ventura will certainly feel confident of enhancing his reputation even further by seeing off a weakened South American outfit.
With Luis Suarez out injured and Edinson Cavani also struggling to recover from a knock picked up in Sunday’s defeat in Ireland, La Celeste will surely struggle to end a run of four consecutive defeats when they take on their in-form opponents.
All things considered, those 23/20 (2.15) odds seem like excellent value on a confident Italy proving too strong for an understrength and out of sorts Uruguay.