Three points clear of the Swedes at the top of their qualification group, Didier Deschamps' men are available at 2/7 (1.29) with bet365 to travel to Solna in high spirits by coming out on top here.
With their own chances of making it to Russia looking slim as they sit five points adrift of South America's automatic qualification places with four games to play, La Albirroja are on offer at 10/1 (11.00) to give themselves a major boost with victory in Rennes.
Each of the last three encounters between these sides have finished all square after 90 minutes, and you can get odds of 4/1 (5.00) on them playing out another draw in this one.
While former defender Francisco Arce will have fond memories of taking the eventual champions into extra-time in a 1-0 last 16 defeat at the 1998 World Cup, he will not be holding out much hope of overseeing a similar performance when he returns to French soil as coach almost 20 years later.
Having seen his side lose five of their last seven matches, it certainly seems unlikely that they could pull off a shock victory against a side that has won 12 of their last 14 and lost only to Spain in that period.
In fact, considering the South Americans have only scored twice in their last eight fixtures played away from home, the margin of victory should be fairly comfortable for Les Bleus.
With a frontline boasting the talents of Antoine Griezmann, Alexandre Lacazette and new Monaco star Kevin Mbappe, odds of 4/5 (1.80) seem rather generous on France winning by at least two clear goals against a Paraguay team that has conceded nine times in their last four matches.