The 19-year-old defender has made three outings for the Three Lions at U-21 level, but will make a step up in a final fixture before Gareth Southgate’s side head to Russia.
Alexander-Arnold is one of several changes made by England to the side which edged out Nigeria 2-1 in their last outing.
With Southgate eager to take a look at as many players as possible heading into a major tournament, those on the fringes of the fold have been given an opportunity to impress at Elland Road.
Leicester striker Vardy is unlikely to dislodge prolific captain Harry Kane from a starting berth, but he will get the chance to enhance his international goal record against Costa Rica.
Manchester United’s Marcus Rashford will also be hoping to catch the eye in a central striking berth.
Ruben Loftus-Cheek has impressed in his England outings to date and can prove to Chelsea that he is deserving of a chance in 2018-19.
At the back, Leicester’s Harry Maguire comes back in, while Danny Rose replaces Ashley Young at left-back and Jack Butland gets the chance to stake a claim for being the first name on the team sheet.
England team: Butland; Rose, Stones, Maguire, Jones, Alexander-Arnold; Delph, Henderson, Loftus-Cheek; Rashford, Vardy.
Costa Rica team: Navas; Gamboa, Waston, González, Calvo, Oviedo; Venegas, Guzmán, Borges, Campbell; Urena.
The rest of England’s 23-man World Cup squad will be available to Southgate from the bench, while those on standby – Tom Heaton, Adam Lallana and Jake Livermore – will also take up a position among the substitutes.