The Seagulls striker contested a header with Federico Fernandez, and the Newcastle defender inadvertently made contact with the back of Murray's head.
Murray hit the ground, seemingly unconscious, and both his team-mates and opposition players immediately called for treatment to be administered.
Doctors spent six minutes tending to Murray, and he was eventually stretchered off with an oxygen mask over his face.
The 35-year-old was taken straight to hospital, and Jurgen Locadia came on as a substitute to replace him.
Murray was applauded by both sets of supporters as he was substituted, and Brighton will hope that his injury is not too serious.
The Seagulls have confirmed that their striker is set to undergo "precautionary scans".
Indeed, he also enjoyed a superb 2017-18, netting 14 goals in all competitions, and was tipped as a potential wildcard for Gareth Southgate's England squad at the World Cup.
Nevertheless, Brighton took the lead following his substitution, as Biram Kayal tapped home Jose Izquierdo's effort.