Paul Pogba has been included in the Manchester United starting XI by Jose Mourinho for Sunday's Premier League fixture at Sunderland.
Elsewhere, Luke Shaw starts for only the third time in over four months at left-back while Matteo Darmian comes in at right-back for the first time since January. Sergio Romero relieves David de Gea in goal and Antonio Valencia is again rested.
United head into the game sitting sixth in the Premier League table, seven points adrift of the Champions League places.
A win will see them move above Arsenal, though, with the Gunners not in action again until Monday evening.
Sunderland are in desperate need of a win as they look to reduce the 10-point gap which separates them from Premier League safety.
Sunderland: Pickford, Jones, Oviedo, Denayer, Cattermole (captain), Larsson, Rodwell, Ndong, Defoe, Kone, Anichebe.
Subs: Mannone, Djilobodji, Borini, Khazri, Manquillo, Pienaar, Gibson.
Man Utd: Romero, Darmian, Bailly, Rojo, Shaw, Fellaini (captain), Herrera, Pogba, Mkhitaryan, Ibrahimovic, Lingard.
Subs: Pereira, Tuanzebe, Fosu-Mensah, Blind, Carrick, Martial, Rashford