Zinedine Zidane's men are shuffling towards the end of a season where they are likely to finish third in the table and without any major silverware.
The visitors to the Spanish capital meanwhile are hoping to secure European football and Gaizka Garitano's side are in good form having won four of their last five league games.
Madrid have won their last three home league matches albeit with some underwhelming performances. Another victory for Los Blancos is available at 1/2 (1.50) with bet365.
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Madrid captain Sergio Ramos missed the last game against Leganes with a calf injury and is likley to remain sidelined, along with winger Vinicius Junior.
Toni Kroos was also missing against Leganes and has not trained much this week with gastroentirits so the German is also a doubt, while striker Mariano Diaz is definitely out. The visitors will be without injured wideman Ibai Gomez.
Some Madrid players have admitted it is difficult reaching the final part of the season with nothing on the line and there has been a lack of intensity in some of their recent performances.
Athletic for their part have found their scoring touch in the last few weeks, with forward Inaki Williams in particularly impressive form netting five goals in his last five appearances.
The visitors will feel like they can score against a stuttering home side and there should be interest in backing Athletic to get on the scoresheet.
Tips and predictions
Zidane's men have conceded 21 first half goals this term, with only three sides conceding more, although only Barcelona have scored more times than Madrid in the opening 45 minutes.
Backing goals in the first half therefore makes perfect sense and there could also be some interest in the price of 6/5 (2.20) for over 1.5 goals first half.
Odds correct at the time of writing. Please gamble responsibly.