Zinedine Zidane's side still lead La Liga by a point from fierce rivals Barcelona despite having played two fewer fixtures than the Catalans (one because of their participation in the Club World Cup in December and the other due to last weekend's postponed fixture).
By the time they kick off in Pamplona on Saturday evening, Los Blancos will not have played a competitive fixture in two whole weeks, while they could find themselves provisionally behind Barca in the table if the Catalans win at Alaves.
REAL MADRID INJURIES
However, the two-week break has allowed Zidane to recover his other injured players, with Dani Carvajal and Luka Modric now fully fit again, and the Welsh winger is the only one sidelined for the trip to Pamplona on Saturday.
REAL MADRID SUSPENSIONS
Toni Kroos is still suspended. The Germany midfielder was set to serve his ban in the match at Celta Vigo last weekend, but will now miss out against Osasuna instead after the game at Balaidos was postponed.
REAL MADRID POTENTIAL STARTING LINE-UP
Zidane is set to name a strong side for the trip to Osasuna on Saturday, despite the continued absence of Bale through injury and Kroos' suspension.
With the Champions League last-16 first leg match against Napoli ahead on Tuesday, the French coach may decide to keep the recently recovered Luka Modric and Dani Carvajal in reserve on Saturday.
Marcelo is certain to be back, meanwhile, while James Rodriguez could also feature from the start after joining in the match with the other first-team regulars in training on Friday.
OSASUNA TEAM NEWS
Osasuna are stranded at the foot of La Liga and need a miracle to avoid relegation even at this stage of the season.
The Pamplona-based side have claimed only 10 points so far from their 21 fixtures and are eight adrift of 17th-placed Leganes.
The northerners lost 5-2 at the Santiago Bernabeu earlier this season and have a number of players out injured. Javier Flano, Miguel Flano, Didier Digard and Nauzet Perez are all sidelined with long-term problems, while Mario Fernandez is doubtful after missing the 3-2 loss at Real Sociedad last weekend.
BEST OPTA MATCH FACTS
Osasuna are winless in their last 13 Liga games (drawn four, lost nine), their worst-ever run in the Primera Division.
Real Madrid have failed to win on each of their last two visits to Pamplona in La Liga (both draws), with their last triumph there coming in 2012 when they won 5-1 (their biggest away win at Osasuna).
Cristiano Ronaldo has scored eight goals in his last five appearances against Osasuna in La Liga.
Oriol Riera has scored three goals in his three games against Real Madrid in La Liga, with all three coming via headers.
TV COVERAGE & KICK-OFF TIME
Osasuna versus Real Madrid kicks off at 20:45 CET on Saturday at El Sadar and will be televised live on Sky Sports 1 from 19:15 GMT.