The top two Kenyan Premier League sides will clash on Sunday at the Kenyatta Stadium in Machakos.
But Mathare, who are two points behind the league leaders, has been hit by a major blow following the news that the 2017 defender of the year will not be availed for the clash.
Owino limped out in 1-0 defeat to Wazito last time out with a toe injury with medical reports showing a fractured metatarsal that will keep him out for approximately a month.
“He has a fracture that will take approximately three weeks to heal. He should be back in a month’s time,” Mathare United senior physiotherapist Wycliffe Omom told the club website.
But even on his sick bed, Owino has tipped the squad to bounce back to winning ways and make a big statement with a win over the defending champions.
“We have put the losses behind us and we are motivated to rekindle our good start to the season. We cannot afford to lose against Gor Mahia.”
Mathare lost the last two games and another slip up against K’Ogalo will have a severe dent in their chase for a second KPL title.
Mathare will also be without head coach Francis Kimanzi who was sent to the stands in the last match.
The only good news from the slums, though, is the return to action of goalkeeper Robert Mboya who resumed training this week.