The two sides meet in the country's National Stadium, with the clash given an extra flavour by the mounting speculation over Red Devils striker Romelu Lukaku's potential departure to the San Siro club.
But their Italian opposition represent a different challenge, even if the Nerazzurri have never beaten United in a competetive encounter before.
|Game||Manchester United vs Inter|
|Date||Saturday, July 20|
|Time||12:30pm BST / 7:30am ET|
TV Channel, Live Stream & How To Watch
In the United States (US), the game will be broadcast on ESPN2. It can be streamed via ESPN Deportes+.
|US TV channel||Online stream|
In the United Kingdom (UK), the game will be broadcast on MUTV. It can be streamed via MUTV.com.
|UK TV channel||Online stream|
Squads & Team News
|Position||Manchester United squad|
|Goalkeepers||De Gea, Grant, Pereira, Romero|
|Defenders||Dalot, Wan-Bissaka, Bailly, Jones, Lindelof, Rojo, Smalling, Tuanzebe, Shaw, Young|
|Midfielders||Chong, Garner, Gomes, James, Lingard, Matic, Mata, McTominay, Pereira, Pogba|
|Forwards||Greenwood, Lukaku, Martial, Rashford|
Man Utd XI: De Gea; Wan-Bissaka, Lindelof, Tuanzebe, Shaw; Lingard, Matic, Pogba; James, Rashford, Martial
|Goalkeepers||Berni, Handanovic, Padelli|
|Defenders||Bastoni, D'Ambrosio, Dalbert, De Vrij, Ranocchia, Skriniar, Ntube, Pirola|
|Midfielders||Agoume, Barella, Borja Valero, Brozovic, Candreva, Gagliardini, Joao Mario, Lazaro, Nainggolan, Perisic, Sensi|
|Forwards||Longo, Politano, Colidio, Esposito, Vergani.|
Inter XI: Handanovic; D’Ambrosio, De Vrij, Skriniar; Dalbert, Sensi, Brozovic, Gagliardini, Candreva; Longo, Esposito
Betting & Match Odds
Manchester United can be backed at 21/20 to win this game with bet365. Inter are priced as outsiders at 12/5 while a draw is available at 13/5.
Manchester United will be hoping to put any off-field speculation and distraction behind them when they face Inter at Singapore's National Stadium this weekend - but given the consistent transfer rumours enveloping the two clubs, that may be easier said that done.
Red Devils forward Romelu Lukaku has been linked with a move to the Serie A outfit ever since the transfer window opened at the close of last season, and the Belgium international is widely tipped to make his way to Italy after the conclusion of United's pre-season commitments in Asia.
All eyes will be on whether the striker features for Ole Gunnar Solskjaer's team against Antonio Conte's men in the 2019 International Champions Cup, after he was absent from their midweek win over Leeds United in Australia.
The Norwegian may have already found a winning replacement however in teenager Mason Greenwood, who has enjoyed a fine pre-season tour so far, leading to his manager offering up effusive praise of his skills ahead of an additional ICC match against Tottenham in Shanghai next week.
"You can see we’ve got a talented boy there and he’s every opportunity to make it as a Manchester United player," he said.
"Of course, it’s also going to be about luck. He must stay clear of injuries, be professional and I’m sure he’s going to grab his chance. Everything is there for him"
Defender Alessandro Bastoni, a former graduate of Atalanta's youth ranks, who has spent the last two seasons away on loan from the club, is hoping to make 2019-20 his breakthrough campaign.
"It’s an honour for me to represent these colours," he told the media in Singapore. "I’ve been hoping to reach this point for two years now and I’ve finally got this opportunity.
"It’s certainly the case that I’ve immediately been made aware of where I am. Working with high-quality staff and great players is a great honour and privilege for me, and I’ll try to learn as much as possible."