The hosts can move level with Antonio Conte's side and potentially into the top four with victory, while a win for the Blues could see them leapfrog Manchester United into second, depending on results elsewhere.
Both teams come into the game having been in Champions League action during the week, but, while Chelsea recorded an emphatic 4-0 win over Qarabag, Liverpool were left deflated as they relinquished a 3-0 lead to draw 3-3 away to Sevilla.
|Game||Liverpool vs Chelsea|
|Date||Saturday, November 25|
|Time||17:30 GMT / 12:30 ET|
TV CHANNEL & LIVE STREAM
In the United Kingdom (UK), the match will be available to watch live on television on BT Sport 1 and by live stream using the BT Sport app.
|UK TV channel||Online stream|
|BT Sport 1||BT Sport app|
In the United States (US), the match will be available to watch live on television on NBC and it can also be watched by live stream using the NBC Sports app.
|US TV channel||Online stream|
|NBC||NBC Sports app|
SQUADS & TEAM NEWS
|Defenders||Lovren, Gomez, Klavan, Moreno, Robertson, Matip, Flanagan, Alexander-Arnold|
|Midfielders||Wijnaldum, Milner, Coutinho, Henderson, Grujic, Lallana, Oxlade-Chamberlain, Can, Brannagan, Markovic, Ejaria, Wilson, Paulinho|
|Forwards||Firmino, Sturridge, Solanke, Salah, Mane, Ings, Brewster, Woodburn|
Joel Matip is expected to be available for selection after sitting out the mid-week Champions League clash against Sevilla, but Adam Lallana is still a few weeks away from full fitness.
Nathaniel Clyne is still out of action as he recovers from surgery undertaken to correct a back injury.
Potential Liverpool starting XI: Mignolet; Moreno, Matip, Lovren, Gomez; Henderson, Can, Coutinho; Salah, Mane, Firmino.
|Goalkeepers||Caballero, Courtois, Eduardo|
|Defenders||Rudiger, Alonso, Zappacosta, Cahill, Christensen, Azpilicueta, Luiz, Clarke-Salter, Sterling|
|Midfielders||Fabregas, Drinkwater, Kante, Hazard, Pedro, Bakayoko, Moses, Willian, Scott, Ampadu, Kenedy|
Victor Moses is expected to be available for selection following his recovery from a hamstring injury, but there are doubts over the fitness of Charly Musonda and Kenedy.
Michy Batshuayi, meanwhile, is also out of action after sustaining an ankle injury while on international duty with Belgium.
Potential Chelsea starting XI: Courtois; Azpilicueta, Cahill, Luiz; Zappacosta, Alonso, Kante, Fabregas; Hazard, Pedro, Morata.
BETTING & MATCH ODDS
Home side Liverpool are favourites to win at 23/20 according to dabblebet , with Chelsea priced at 12/5 to defeat the Reds. A draw between the sides at Anfield is a 5/2 bet.
Roberto Firmino, Mohamed Salah and Alvaro Morata are all rated 4/1 to open the scoring on Saturday.
Despite the nature of their draw against Sevilla during the week, Liverpool come in to their game against Chelsea on a five-game unbeaten streak and will have plenty of belief in their ability to overturn Conte's champions, especially given the attacking riches at their disposal.
Chief among their star attackers is former Blue Mohamed Salah, who will no doubt be eager to show his old club what they are missing as he endeavours to stretch his lead at the top of the scoring charts. Salah has scored five goals in his last four games in all competitions and moved ahead of Harry Kane in the Premier League charts with a double against Southampton last week.
Chelsea are also on an unbeaten run, albeit just three games, but they arrive at Anfield brimming with confidence following successive victories over Man United, West Brom and Qarabag. The burgeoning partnership between Alvaro Morata and Eden Hazard is beginning to yield rewards and the pair were particularly impressive in the 4-0 win over the Baggies at the Hawthorns.
While the home side boast incredible talent going forward, their fragile defence has been their undoing and, Conte will be keen to exploit that obvious weakness. Indeed, while Liverpool have lost fewer league games than Chelsea this season, their only losses have come against top-four sides (4-1 against Tottenham and 5-0 against Manchester City), so they will have to work extra hard to avoid yet another disappointment.