Naby Keita is set to undergo tests after sustaining an adductor problem in RB Leipzig's win at Hamburg on Friday.
After opening the scoring past the hour-mark, Keita – who will join Liverpool in the Premier League next season – had to leave the field in the final minute of regulation.
Germany international Timo Werner was also on target as Leipzig ended Hamburg's unbeaten start, sealing the victory with 15 minutes remaining.
Werner, though, could have opened the scoring in the first half after being awarded a penalty.
However, the video assistant referee (VAR) overturned the decision, after Werner went down in the box under a challenge from Albin Ekdal.