The situation amplifies the importance Sunday morning's [AEDT] blockbuster between Spurs and the Blues at Wembley - with the duo currently four and five points behind City respectively.
A loss to either side will severely dent their already small chances of being title contenders and thrust them into a battle with Arsenal for a top four position.
Spurs will host the match at the England national team stadium - their temporary home during the redevelopment of White Hart Lane - and it's a venue they have struggled at this season.
Only six of Tottenham's 26 Premier League points have been won at Wembley this season, with Mauricio Pochettino's team excelling on the road.
On the flip side, Maurizio Sarri's Chelsea have only conceded one goal on their travels and will be primed to take advantage of Tottenham's Wembley wobbles.
Spurs' recent form against Chelsea has been solid - winning three of their past seven league matches - which is a significant improvement from the three wins in their 49 Premier League duels previous to that.
Tottenham expected to be moved into their new stadium by this stage of the season, with the club requesting to play more away games to open the campaign.
Having played eight of their first 12 Premier League matches away from home, Tottenham's fourth position in the league is fairly respectable.
The club has won their past four matches in all competitions with Harry Kane scoring three goals in that run of games - to go with his recent winner for England against Croatia in the Nations League.
However Chelsea's form line is more impressive, having yet to lose a game this season under Sarri, who arguably has them playing the most attractive football in the league.
Their star man Eden Hazard has scored seven league goals this season and looms as the player Tottenham need to stop.