Nairobi City Stars will play host to FC Talanta later on at 4.15 pm.
Ushuru are top of the table with 38 points, just one above Stima after 19 rounds of matches.
KCB one place and two points behind third-placed Nairobi Stima who will travel to Western to take on Green Commandos at Bukhungu Stadium on Sunday.
Fifth-placed Bidco United will also have a chance to break into the top four should they sail past Kibera Black Stars and hope that KCB falters.
Friday Fixtures: KCB vs Modern Coast Rangers (Camp Toyoyo, 2 pm) LIVE on Bamba Sports, Nairobi City Stars vs FC Talanta (Camp Toyoyo, 4.15 pm) LIVE on Bamba Sports.
Saturday Fixtures: St. Joseph’s Youth vs GFE 105 (Afraha Stadium, 1 pm), Kisumu All Stars vs Coast Stima (Moi Stadium Kisumu, 3 pm), Kangemi All-Stars vs Nakuru All-Stars (Ruaraka Grounds, 4 pm), Ushuru vs Western Stima (Ruaraka, 4.15 pm).
Sunday Fixtures: Green Commandos vs Nairobi Stima (Bukhungu Stadium, 3 pm), Kibera Black Stars vs Bidco United (Hope Center, 3 pm), Isibania vs Administration Police (Awendo Green Stadium, 3 pm).