Top of Group F with nine points from nine, Pep Guardiola's men are available at 6/4 (2.50) with Betfair Sportsbook to progress to the last 16 with two matches to spare by maintaining their 100 per cent record here.
A draw would also be enough to see the visitors progress to make it through to the next stage, and there are odds of 29/10 (3.90) on offer on them settling for a single point.
Picked as one of the ties of the round between two of Europe’s in-form teams, the encounter at the Etihad Stadium certainly lived up to its billing.
While the Citizens struck twice within the opening 15 minutes, they had an Ederson penalty save to thank for maintaining their two-goal lead at half-time before eventually holding out to win 2-1.
Indeed, Guardiola was quick to label the Italians the best team his side had faced this season, so impressed was he by their quality on the ball.
Having scored three goals or more in five of their last six home matches, Maurizio Sarri’s men will back themselves to pose even more of a threat going forward back in front of their own fans.
Averaging three goals per game themselves this campaign, the Citizens will also feel confident of playing their part in what promises to be another high-scoring affair.
All in all, odds of 6/5 (2.20) offer strong value on over 3.5 goals being scored for City’s ninth Champions League away game in 12, as well as Napoli’s fifth in seven on home turf.