Antonio Conte’s charges had to settle for a share of the spoils at home to Parma over the weekend, the second time they dropped points this season.
Asamoah was rested on that occasion but was back in place of Cristian Biraghi, and it was the strong strike partnership of Lautaro Martinez and Romelu Lukaku which scored in either half before the visitors clawed one back via a Milan Skriniar own goal.
It proved to be only a consolation with Inter taking home all the points.
Asamoah was substituted in the 81st minute for Biraghi, making 19 key passes (70.4% accuracy) with 47 touches.
The former Juventus wing-back was also successful in his three dribbles as well as his sole aerial duel, while winning four of eight ground duels. He made three clearances.
Inter are now back to the summit of the log, but will be hoping Juventus drop points when they host Genoa on Wednesday night.