The Italian has repeatedly complained of a 'strange mentality' and 'lack of determination' from his players and was most angry with his team's performance in an away defeat to Wolves.
He is keen to capitalise on the win over Man City, to win against teams outside the top six but Chris Hughton's side will be tough opposition due to their impressive start to the season sitting in mid-table.
Chelsea have rested a host of players due to a dead rubber mid-week Europa League clash against MOL Vidi. The likes of Eden Hazard, N'Golo Kante, Kepa Arrizabalaga, Antonio Rudiger and Cesar Azpilicueta were all left at home.
Alvaro Morata picked up a knock in Budapest but Sarri told journalists after Thursday's game that 'the first impression of the doctor maybe it is not a serious injury.' However, Morata remains a doubt for Chelsea.
Three other players stayed in England due to physical problems including Mateo Kovacic, who appeared to get a thigh strain and came off against Man City. Sarri also said that fringe players Victor Moses and Gary Cahill were left out of the last game due to injury.
Cahill may see limited game time until the end of December and Sarri comfirmed in his pre-match press conference that a January move looks likely for the former England international.
"I respect him very much because he has won everything with this club," Sarri told reporters. I have to do my job. Every match, I have to choose. For me, he is not able to [be] on the bench.
"Maybe he is the best in the box, but our defenders may play 100 or 110 balls in a match so I need very technical defenders."
On the possibility of Cahill leaving, he added: "It is not my decision, but it is up to him and the club."
Chelsea have no players suspended for the match but Shane Duffy is out for Brighton. N'Golo Kante, Alvaro Morata, Jorginho and Antonio Rudiger have the most bookings this season for the Blues, with three apiece.
Chelsea Potential Starting Line-Up
Chelsea rested a whole host of stars in the 2-1 Europa League win over MOL Vidi in Budapest and they are now likely to start XI different players against Brighton.
Sarri has prioritised the Premier League over the European group stage this season, after the Blues got a fairly easy group and won it with two games to spare.
Chelsea have made fewer changes in the Premier League than any other team in the league, except for Wolves. They will play their strongest possible line up in the away trip to the Amex Stadium.
Kovacic's injury may see either Ruben Loftus-Cheek or Ross Barkley come in to replace him after he started last weekend.
Brighton Team News
Club-record signing Alireza Jahanbakhsh looks likely to be absent and has missed the last five matches for Brighton. José Izquierdo is a doubt after picking up a knock.
TV channel & kick-off time
The match at Stamford Bridge kicks off at 1:30pm GMT (8:30pm ET) on Saturday but it won't be shown on TV in the UK.
Best Opta Match Facts
Chelsea have won each of their six games against Brighton in league competitions; their best 100% record against a single opponent in league history.
Brighton are looking for their first victory against Chelsea in any competition since January 1933, when they won 2-1 in an FA Cup third-round tie.
Brighton have lost just one of their last 10 home Premier League games (W5 D4). However, 80% of their home defeats in the competition have been against ‘big six’ opposition (4/5).
While only Wolves (18) have used fewer players in the Premier League than Chelsea this season (20), no side has had more different goalscorers than the Blues (12). A league-high 60% of players to play for Chelsea in the Premier League this season have scored.
Chelsea’s Eden Hazard has provided an assist in each of his last three Premier League games (4 assists in total). He’s never assisted a goal in four consecutive games in the competition before, with Cesc Fabregas in September 2014 the last player to do so for Chelsea.