The Citizens went down 2-1 at home to France’s third-placed side in midweek, but have taken 13 points from 15 in the league so far.
Undefeated in 21 matches against newly-promoted teams, they are clear 1/6 (1.17) favourites with bet365 to get straight back to winning ways in the Welsh capital.
However, the home side recorded a memorable 3-2 victory when the teams last met at the Cardiff City Stadium in the league in 2013, and are available at 14/1 (15.00) to pull off another upset five years on.
Sergio Aguero could return to the line-up after starting on the bench against Lyon following an injury, with Benjamin Mendy also hoping to return from his own lay-off with a knee problem.
Josh Murphy, Harry Arter and Aron Gunnarsson all face late fitness tests, while Nathaniel Mendez-Laing is a long-term absentee.
Those two previous matches have produced 10 goals, with Warnock explaining that he would rather give the fans some entertainment by showing some ambition rather than sitting back and hoping to kill the game.
Having conceded seven of those 10 goals and picked up zero points, the Bluebirds could be in for another chastening match against a City side determined for a reaction after the Lyon game.
With 11 goals scored in the two previous league encounters between this pair, odds of 6/5 (2.20) seem generous on Cardiff coming away empty-handed from a match featuring over 3.5 goals for their fourth successive outing in all competitions.
Odds correct at the time of writing. Please gamble responsibly.