Unsurprisingly, the bookmakers make Manchester City favourites to win the first piece of domestic silverware this season.
The issue for punters will be finding value in what is a market already expecting a high-scoring home win - and rightly so.
Over 3.5 goals is well odds-on at 13/20 (1.65) and that's understandable given City's firepower but also the visitors' woeful defensive record.
Slavisa Jokanovic has already seen his side concede 28 times in just 10 top-flight matches, by far the worst tally of any team in the division.
The way to go here looks to be backing a home win but adding in the stipulation that both teams find the net. That's an industry-best 7/4 (2.75) with 888Sport at the time of writing.
Fulham do have plenty of attacking options and given the increasing pressure on Jokanovic, the Cottagers' boss will expect a response from his side, even with a relative mountain to climb in the tie.
Without the pressure of their increasingly poor league position, there should be a freedom about the visitors that we haven’t seen for a few weeks.
City's squad is extremely deep of course, but changes are expected and that lack of continuity in a defensive unit should allow the visitors some opportunities to make their mark.
It's difficult to see past a relatively straightforward home win and while correct score plays such as 4-1 at 12/1 (13.0) are worth a small stake, the main bet should be the 7/4 (2.75) with 888Sport on City coming out on top in an open encounter at the Etihad Stadium.