Ernesto Valverde's side have won 10 of their 11 games so far in the Primera Division and drew the other, away to Atletico in October.
Here, everything you need to know about Barcelona's trip to Leganes earlier in the day...
Ousmane Dembele is still sidelined with a thigh injury, but the French forward could be back earlier than expected and may feature in the Clasico against Real Madrid before Christmas.
Sergi Roberto, Andre Gomes and Rafinha are all still sidelined, while Javier Mascherano also misses out after picking up an injury on international duty with Argentina.
Barcelona have no players suspended for the game against Leganes, but Gerard Pique and Samuel Umtiti both have four bookings in La Liga this season and are one card away from a ban.
BARCELONA POTENTIAL STARTING LINE-UP
Barcelona boss Ernesto Valverde will hope centre-backs Gerard Pique and Samuel Umtiti are on their best behaviour as both are just one booking away from a ban that would see them miss the trip to in-form Valencia next weekend.
However, with Javier Mascherano sidelined, Valverde does not have too many options in that position, although he could consider starting Thomas Vermaelen to rest one of his two first-choice centre-backs ahead of the Champions League clash away to Juventus on Wednesday.
Further forward, Paco Alcacer is set to feature after he scored both goals in the 2-1 win over Sevilla before the international break.
LEGANES TEAM NEWS
Leganes have made a strong start to their second season in La Liga, after finishing in 17th place last term.
The Madrid-based side are currently in ninth position, with 17 points from their 11 matches, including five wins. However, Asier Garitano's men have lost their last two games in the Primera Division, going down 2-1 at Sevilla and 3-0 away to Valencia.
Goalkeeper Jon Serantes is still sidelined with a long-term injury, while Omar Ramos is doubtful.
BEST OPTA MATCH FACTS
Leganes have lost their two competitive games against Barcelona, scoring only two goals and conceding seven. Both matches were in La Liga last season.
Leganes have conceded more goals in their last two league games (five) than they had in their previous nine this season (three).
Barcelona have let in just four goals in La Liga this season, their best ever start in terms of goals conceded. Only one team conceded fewer in the first 11 games of a Liga season (three, Atletico in 1995-96).
Lionel Messi has scored four goals in his two games against Leganes in La Liga. The Argentine is the player with the most goals scored against Leganes in La Liga, alongside Alvaro Morata.
Luis Suarez has failed to score in his last five games in all competitions. He has never gone six in a row without scoring for Barcelona.
TV COVERAGE & KICK-OFF TIME
Leganes versus Barcelona kicks off at 16:15 local time at Butarque on Saturday. British broadcasting laws mean games cannot be aired live at that time on a Saturday, but the match will be shown later, from 17:30 UK time on Sky Sports Mix.