Howe told reporters on Friday: "[Isak] won't be part of the squad this weekend. The club has to act in the best interests of Newcastle United. It will do that in every situation It looks like it is coming to an end, or it will come to an end pretty quickly."
THE BIGGER PICTURE
Isak appeared to rule out a Newcastle return after accusing the club of "breaking promises", something the Magpies were "disappointed" by. The Reds are yet to return with an improved offer after their initial £120 million ($162m) bid was rejected. An intriguing last week or so of the transfer window lies ahead.
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WHAT NEXT?
While Isak will not feature for Newcastle in their next Premier League encounter, football fans will be eager to see whether or not the former Real Sociedad man will line up against Leeds United on August 30, with the summer transfer window closing on September 1.