While domestically the side have disappointed, there is still a chance for Los Blancos to make history in next weekend's Champions League final by winning it for the third time in a row.
Their trip to Villarreal on Saturday evening will likely be little more than a training session for the showdown in Kiev, given both sides have nothing to play for.
Villarreal recorded a famous 1-0 win at the Santiago Bernabeu back in January, and dabblebet offer them at 6/4 (2.50) to claim another victory.
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Cristiano Ronaldo has missed the last couple of games for Real Madrid since picking up an injury in the Clasico and it remains to be seen if he features at all in Villarreal.
Zinedine Zidane is likely to rest senior players ahead of next weekend's clash with Liverpool, and the manager may use the final La Liga game of the season to give some minutes to some younger members of the squad.
Villarreal have no new injury concerns.
For the first time in nearly a century there is nothing at stake on the final weekend of the La Liga, with everything already decided.
Villarreal have guaranteed themselves automatic qualification to the Europa League, with four wins in their last five matches enough to ensure a top six finish.
The Yellow Submarine have beaten both Atletico Madrid and Valencia in their own stadium recently, though, and although there is nothing but pride at stake, they are capable of competing against a distracted Real Madrid side.
Tips and predictions
With little at stake this game is likely to be very open with an end of season feel to it. This makes the winner harder to call, but both teams to score and either to win appeals at 8/11 (1.73).