In tradtionally one of the toughest away games of the season, Barca produced a solid display against Athletic Bilbao in San Mames to win 2-0, with excellent performances from goalkeeper Marc Andre Ter-Stegen and Lionel Messi.
In the tenth league match of the season, Ter-Stegen kept his seventh clean sheet, while Messi scored his twelfth league goal and both players will be confident of continuing their strong form on Tuesday night.
Olympiakos, meanwhile, are enduring one of their worst starts to a league campaign in recent memory and Saturday saw them lose their fierce cross-city derby against Panathinaikos.
After nine matches, the Pireaus outfit have already lost three league games and conceded eleven goals, and given that they lost just five times and conceded 16 goals in the whole of the previous season, something is clearly not right.
It could therefore be a pretty tough night for the Greek champions, and bet365 offer them at 12/1 (13.00) to claim three points, while Barca can be backed at 1/5 (1.20) and the draw is offered at 11/2 (6.50).
Two weeks ago in the Camp Nou, Barcelona easily triumphed 3-1 despite having Gerard Pique sent off in the first half, and our selection on that night proved profitable as we went for 4-6 goals in the game, while Saturday saw us collect more profit backing Barca to win by two goals or more in Bilbao.
For Tuesday evening, betting on the La Liga leaders to score over 2.5 goals at 5/6 (1.83) seems an extremely solid option, with the Greek defence looking far from convincing; Olympiakos have conceded three goals in three of their last four home group games, with Bayern Munich, Arsenal and Sporting Club all netting over 2.5 goals in their trips to Pireaus over the last couple of years.
This bet has paid out in eight of Barca's last 12 games in all competitions and with Messi in superb form, the Catalans should be able to inflict more misery on their out of form opponents.