The two sides could not be in more contrasting form, with Ernesto Valverde's men unbeaten all season and eight points clear.
Malaga, meanwhile, have lost their last six matches and are winless in three months.
That being said, Malaga won this fixture 2-0 last season and boast a decent record against the Catalans with two wins and two draws in the last seven games between the sides.
They remain massive outsiders, though, for Saturday's clash with dabblebet pricing them at 11/1 (12.00).
Andres Iniesta is missing for the Blaugrana having picked up an injury last weekend, while Nelson Semedo also remains unavailable.
Malaga, for their part, are likely to be without midfielders Adrian Gonzalez and Recio.
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Feeble Malaga attack
Since the turn of the year Malaga, have played ten league matches and only scored three goals.
That damning statistic explains why the Andalusians find themselves rooted to the bottom of the table, eight points from safety.
Barca's defence, meanwhile, has been rock solid this term with just 13 goals conceded in 27 games and against a team as goal shy as Los Boquerones, the Catalans should be able to record a win with few problems.
Tips and predictions
The price of 10/11 (1.91) for Barcelona to win to nil is extremely tempting, given the statistics of the respective sides.
Barca have the best defensive record away from home in the division and against a team devoid of goals, this selection should pay out for a ninth time on the road this season for the leaders.