Having won each of their three league matches since a shock 2-1 defeat to Newcastle, Pep Guardiola's side are now 8/11 (1.73) favourites to retain their domestic crown.
The high-scoring win at the Etihad Stadium not only moved City level with Liverpool on points - albeit they've now played a game more than the Reds - but also strengthened the reigning champions’ goal difference which now stands at 10 more than their nearest rivals.
Liverpool are 6/5 (2.20) in bet365's latest Premier League odds after easing past Bournemouth the previous day - their first victory in three games having drawn with West Ham and Leicester City. Jurgen Klopp's side have a game in hand but it comes in the form of a trip to the resurgent Manchester United on Sunday February 24.
The Merseysiders should be well-rested for the visit to Old Trafford, though. Their third round FA Cup exit to Wolves means the Champions League clash with Bayern Munich at Anfield next week is the Reds' only game before that titanic top-flight tussle with United.
bet365 make the visitors 11/8 (2.38) to win that clash while Ole Gunnar Solksjaer's men are priced at 19/10 (2.90) to dent their title hopes. A draw would still give Liverpool a slim advantage over City and that trades at 12/5 (3.40) with the same firm.
Tottenham remain just five points behind the leading duo in the title race after extending their Premier League winning run to four matches against Leicester at Wembley.
Having coped well without Harry Kane and Dele Alli since the pair were sidelined through injury, bet365 go 25/1 (26.0) that Spurs end the campaign top of the table.
Mauricio Pochettino's men face a tough run of fixtures over the next few weeks, though, with trips to Burnley and Chelsea before welcoming Arsenal in the North London derby - just three days before their second leg with Borussia Dortmund in the Champions League.
Manchester United come next in the betting at 250/1 (251.0) having taken 25 points from a possible 27 under Solksjaer since the Norwegian's arrival ,but the Red Devils are still a hefty 14 points behind the leading contenders with just 12 league matches remaining.
Given that United face both Liverpool and their city rivals before the end of the campaign though, they still look set to have a significant say in the destination of the Premier League trophy this term.
Chelsea (1000/1) and Arsenal (1500/1) have rarely looked like genuine title contenders but the London pair will be more concerned with the prospect of missing out on a top four spot, especially with United’s surge up the table in recent weeks.