The Buccaneers will welcome Amakhosi in a massive Premier Soccer League (PSL) encounter at the FNB Stadium in Johannesburg.
The two teams are heading into the first Soweto Derby of the campaign having recorded wins in the Telkom Knockout Cup last weekend.
"Well, it will be another difficult match because both teams secured victories in their previous matches," Chansa told Goal.
"However, the previous results will count for nothing as playing in the Soweto Derby is motivation on its own for the players," he continued.
"This is one of biggest football matches not only in South Africa, but on the continent and a lot of people will be watching this game both locally and in Africa," he indicated.
The former DR Congo international, who was on the books of Pirates between 2004 and 2008, played in several memorable Soweto Derbies including the 2006 Absa Cup final which Chiefs won on penalties.
"I was Pirates' first-choice goalkeeper for four seasons and I know exactly what goes through the players' minds in the field of play," Chansa added.
"This game can either make you or break you. So, one needs to take this big match very seriously and concentrate for the entire 90 minutes," he continued.
Chansa backed the Buccaneers to record their second successive win over Amakhosi, who lost 3-1 in the previous meeting between the two giants of local football.
"Looking at the two teams Pirates are more organised at the back at the moment and they are dangerous when moving forward," he said.
"So, I put my money on Pirates. They will win 2-1 and the victory will serve a much-needed boost for the team for the rest of the season," he concluded.
The last time Chiefs beat Pirates in a league game was almost four years ago.