Dragowski's 17 saves during the 0-0 draw in Bergamo was the most in a Serie A game since 2004-05, when Opta started recording such data.
Atalanta launched a barrage of efforts on Empoli's goal, with captain Alejandro Gomez having nine efforts, Josip Ilicic eight and Duvan Zapata seven.
But they could not find a way past the impressive Dragowski, who helped Aurelio Andreazzoli's side collect a priceless point in their battle against relegation.
Dragowski has started eight matches for the Serie A club this season, having joined on loan from Fiorentina.
The Polish U-21 international has made nine total appearances for Fiorentina since joining in 2016 from Jagiellonia Białystok in his native Poland.
Gian Piero Gasperini's men have now failed to score in their last two Serie A games, having drawn 0-0 away to top-four rivals Inter last time out.