Paris Saint-Germain cruised past Anderlecht 5-0 at the Parc des Princes and remain the 7/2 (4.50) favourites for the Champions League, but three English clubs also enhanced their credentials on matchday four.
Perhaps the biggest result of the round came at Wembley, though, as Tottenham cruised to a 3-1 victory over reigning champions Real Madrid. That was Los Blancos' first group stage defeat since October 2012 and Zinedine Zidane's side have now been eased to 11/2 (6.50) to secure a hat-trick of consecutive titles.
Spurs are 16/1 (17.0) with dabblebet in the outright market after drifting as long as 40/1 (41.0) in places when they were drawn in Group H alongside the holders and Borussia Dortmund - undoubtedly the toughest assignment for any English contender - but are now assured of a spot in the knockout stages with two games to spare.
Barcelona are available at 13/2 (7.50) as the Catalans remain in control of Group D, despite being unable to break down Olympiakos on Tuesday night; Ernesto Valverde’s men have been red-hot in La Liga thus far and have already opened up an eight-point gap to Real Madrid despite the season only being 10 games old.
Bayern Munich come next at 15/2 (8.50), although the Bundesliga giants are likely going to be forced to settle for a runner up spot behind outright favourites PSG in Group B.
Manchester United are priced at 12/1 (13.0) as they kept their perfect record in tact with back-to-back victories over Benfica. Jose Mourinho has plenty of experience in this competition, but does the Portuguese have the squad to make it happen at Old Trafford this season?
Juventus are 16/1 (17.0) alongside Spurs. while Chelsea are out to 22/1 (23.0) following their defeat in Rome but the Blues are still more fancied than Liverpool, who are priced at 25/1 (26.0) by dabblebet ahead of the final two round of group stage matches.