The reverse fixture between Arsenal and Chelsea at Stamford Bridge ended in a 0-0 stalemate earlier this season - a repeat here is 23/2 (12.50) with 888Sport - but the rematch should hopefully provide a more entertaining spectacle.
Antonio Conte's men have proved defensively sound over the festive fixtures though, with the Blues keeping four straight clean sheets in the Premier League since December 16. With that in mind, the Gunners may have their work cut out on home soil and although plenty of big guns will be on show, it could pay to look at one of the other side markets for this game.
Arsenal's attacking options
888Sport make Alexandre Lacazette and Alexis Sanchez both 5/1 (6.0) to make the breakthrough at the Emirates, although the latter certainly makes more appeal given his recent purple patch in front of goal.
While the Chile international continues to be linked with a move to Manchester City before the end of the month, he has struck three times in his last three matches and that doesn't include his free kick opener against West Brom which was ruled an own goal. The 29-year-old is available at 17/10 (2.70) to score during the 90 minutes and that's certainly a tempting option given his recent performances.
Morata to lead the way once more?
Alvaro Morata is the 17/4 (5.25) favourite in the first goalscorer market with 888Sport. Interestingly, six of the Spainard's 10 Premier League goals have been the opening strike of a game so he is definitely a huge runner to consider if you're looking for a bigger price.
The potential for fireworks
One thing this London derby does usually promise is plenty of cards and this clash should be no exception. David Luiz got his marching orders back in September and his red card was the fifth sending off in the last six competitive head-to-head meetings between these two rivals (excludes Community Shield and friendly matches).
With that in mind referee Anthony Taylor should be kept busy at the Emirates and he is not one to keep his card in his pockets either. Although Taylor's last Premier League sending off came in Chelsea's 2-1 win over Stoke City back in March, the 39-year-old official has shown a total of 21 yellows in his last five matches in charge of top flight encounters.
With the recent spate of bad blood between the two sets of players, the 14/5 (3.80) available on another sending off in Wednesday's clash looks worthy of backing with 888Sport.