Asante Kotoko were victors after posting a 3-1 defeat against Medeama in Ghana Premier League matchday 21 at the Baba Yara Sports Stadium on Sunday.
Two first-half goals from centre-backs Ahmed Adams and Evans Quao, unsettled the visitors before Sadick Adams added another through a free-kick while substitute Bismark Oppong scored the consolation for Medeama.
Kotoko made two changes to their starting XI that won the President Cup on Monday. Awal Mohammed, who is on national team duties with the Black Stars B in Togo, and Obed Owusu made way for Richard Osei Agyemang and Evans Quao respectively. Medeama handed former Kotoko goalkeeper Eric Ofori Antwi his first start in seven games ahead of Yaw Ansah while Bernard Ofori and Benjamin Bature led the attack.
The visitors had the first shot on target by the fourth minute after Kwesi Donsu combined with Daniel Ocran but goalkeeper Felix Annan saved the situation.
Sadick threatened Medeama's back-four on several occasions but he was unable to cause any harm. Kotoko finally took the lead by the 13th minute through Quao, his first goal of the season. The defender rose above his marker and headed in a corner-kick from Emmanuel Gyamfi.
The Porcupines nearly made it 2-0 four minutes later after Baba Mahama connected Augustine Sefah's cross but Yaro Ibrahim made a goal-line clearance before Amos Frimpong shot wide moments later.
Bature came close to equalise for Medeama on 25th minute, when he latched onto a pass from Ocran but his last ditch effort was blocked by Frimpong.
Sadick combined with Michael Akuffo on 38th minute in Medeama's box but, the latter's shot was tipped against the woodwork by goalkeeper Antwi. Polack's men finally found the breach to score the second goal through Adams in the resulting corner-kick.
Medeama made a double substitution after the break as Oppong and Agyenim Boateng replaced Bature and Paul Aidoo.
While Medeama were exerting pressure on Kotoko, Sadick curled in a perfect free-kick just outside the visitors' box against the run of play on 67th minute, after Gyamfi was brought down by Samuel Adade.
Annan made double saves on the hour mark to prevent Kwesi Donsu and Tetteh Zutah from finding the back of the net for Medeama.
Oppong finally found the back of the net for the visitors with the last kick of the game when he latched onto a pass from Latif Salifu and sent his effort past onrushing Annan.
Kotoko have moved up to third position with 35 points, five points behind leaders Wafa, who have a game in hand against Ashanti Gold.