Anichebe who has only scored three times in 11 league games for the Black Cats, sustained a knee ligament damage in their 2-0 loss to West Bromwich Albion in January and is expected to be out for 10 weeks.
The former Everton boss lamented on the unavailbality of the forward which has led to a change in formation in his team that sit at the bottom of the Premier League table with 19 points from 25 games.
“I think so [3-5-2 being a solution]. What I do think is it will change. It will change again because of what the opposition can do to you, maybe you’re chasing a game and you need to do it in a different way, you need to look at different things," Moyes told Sunderland Echo.
“But I think when we lost Victor, that was the key to it.
“We needed to keep looking for another way to get up the pitch, to have two forwards playing and not to be too exposed defensively.
“Because we had been making mistakes and conceding goals, I had to make sure we could shore it up a little bit as well.”