The country missed out to France in the battle to host the 2016 competition and TFF president Yildirim Demiroren is confident of succeeding at the second attempt.
"Today we sent our candidacy file to host the European football championships ... to Uefa headquarters," he said in a statement released on his organisation's official website.
"We will make every effort to host the European Championship in Turkey."
With Istanbul bidding to stage the 2020 Olympics, it has been suggested that an attempt to secure two major sporting events in the same year will hinder both campaigns, and Uefa president Michel Platini has previously stated that he will only support Turkey's candidacy for Euro 2020 if they miss out on the Games.
However, while there have been reports of resistance within the Turkish government to backing bids for both the Olympics and the Euros, the TFF insists that there is no division.
"Turkey's Prime Minister, every level of government and every party is aligned behind the bid team and that unequivocal support will remain guaranteed throughout the bid process," the TFF statement read.
"Turkey has already guaranteed that if Istanbul is selected as the host city for the 2020 Olympic Games in September 2013, no other important national or international event will take place in Istanbul or its vicinity around the games period."
The remaining bids for Euro 2020 must all be submitted to Uefa by May 15, with a final decision due in late 2013 or early 2014.
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