Spurs agreed to sign the right-back from Seattle Sounders for £2.5 million in August and immediately loaned him back to the MLS club until the end of the season.
However, Yedlin has since revealed that he could link with the north Londoners once he receives his EU passport, which he qualifies for through his grandmother, and Klinsmann believes that the 21-year-old is a star-in-waiting.
"I think Spurs will get a huge talent," Klinsmann, under whom Yedlin made three appearances at the World Cup, told reporters while in England for his side's friendly against Colombia on Friday.
"We are super excited that he is coming over here. As you saw really quickly in the World Cup, he is highly talented, has great pace, good character, is a good kid and wants to learn.
"So he comes here and he will be a kind of sponge to the coaching staff, to his team-mates and wants, step by step, to break in."