Pitso Mosimane made only two changes to the team that faced Spanish football heavyweights FC Barcelona in a high-profile international club friendly match in Soweto last week.
Razak Brimah and Gaston Sirino made their return to the starting line-up as Sundowns looked to return to winning ways after losing 3-1 to Barcelona having opened their group stage campaign with a 1-1 draw against Moroccan side Wydad Casablanca at home two weeks ago.
On the other hand, Victor Zvuka fielded a strong team as the French tactician looked to mastermind Horoya’s second victory in Group C having defeated Togo’s AS Togo Port 2-1 away a fortnight ago.
Horoya saw most of the ball in the opening stages of the game as they searched for an early goal, but Sundowns' defence looked solid and organized.
However, the hosts were able to penetrate the Brazilians defence twice with the half-hour mark approaching. Dauoda Camara’s glancing header was well-saved by Sundowns goalkeeper Brimah.
The Ghana international was also called into action by his countryman Seyei Baffour, who unleashed a low shot as the hosts pushed for the opening goal.
Sundowns grew in confidence as the match progressed and they had a rare chance when Sibusiso Vilakazi burst into Horoya's box following a mistake by the defence, and he forced keeper Khadim N’Diaye into a fine save.
However, Horoya continued to look dangerous every time they pushed forward and Anele Ngcongca had to produce a world class block to deny Ocansey Mandela from close range with Sundowns defence exposed.
The last chance of first half fell for Sundowns talisman Khama Billiat, but he was quickly denied by N’Diaye, who has been included in the Senegal squad for the upcoming 2018 FIFA World Cup finals in Russia.
The score was 0-0 at the interval following a first half which was dominated by Horoya, but they could not convert their chances.
The hosts continued their dominance after the restart with Sundowns defenders Bangaly Soumahoro and Ngcongca struggling to contain Horoya’s Mandela, who was keeping the visitors’ defence on their toes with his pace and skill.
Mandela was able to beat two of his markers inside the box and he unleashed a shot which beat Brimah, but the crossbar came to Sundowns’ rescue as the South African champions survived a scare.
Horoya deservedly took the lead when Ibrahima Sankhon played a low cross into the visitors’ box and Mandela fired past his countryman Brimah to make it 1-0 to the hosts six minutes into the second half.
The Brazilians had to up their game and they had a chance to level matters through Billiat, who was playing as the targetman with Sirino and Tau playing on the wings, while Vilakazi was deployed just in front of the midfield.
Billiat burst into the Horoya box - controlling the ball brilliantly, before forcing on-rushing N’Diaye into a good low save as the 2016 Champions League winners threatened Horoya for the first time in the second half.
However, Billiat was not be denied in the 69th minute as he scored with a low shot from close range after some great cross by Tau inside the Horoya box after the visitors’ defence was exposed.
The goal boosted Sundowns' confidence as they piled the pressure on the Horoya defence and they were awarded a penalty after Billiat was fouled inside the box by N'Diaye, who was booked for a poor challenge.
Uruguayan winger Sirino then stepped up and made no mistake as he sent N'Diaye the wrong way to make it 2-1 to Sundowns - silencing the home crowd with 11 minutes left on the clock.
However, Sundowns were let down by some poor defending in the closing stages of the game as an unmarked Aboucabar Gal Camara headed home from Brefo Mensah's corner-kick to make it 2-2 a few minutes later.
Horoya then contained Sundowns in the dying minutes of the game and ultimately, the match ended in a 2-2 stalemate.
The draw sees Guinean champions Horoya and South African giants Sundowns remain second and third respectively on the Group C standings after two matches.