There has been plenty of recent history between these two sides, with Real Madrid beating Juventus in each of the last two editions of the Champions League.
That was further added to this summer with Cristiano Ronaldo swapping the Bernabeu for Turin, and while the Portuguese forward will not feature here, there could still be something of an edge to this game which should make it competitive.
Real Madrid captain Sergio Ramos joined up with the squad on Wednesday for his first training session of the summer and could get some minutes on Saturday evening.
Luka Modric, Mateo Kovacic, Raphael Varane, Marcelo and Casemiro remain the only first team players missing from Los Blancos' squad.
Cristiano Ronaldo did not travel with his new team-mates and has begun his pre-season preparations back in Turin.
Juve have already played three matches in the United States this summer and are unbeaten, whilst Real Madrid had their first game on Tuesday night but went down 2-1 to Manchester United.
Julen Lopetegui's men created more chances than United yet lacked match sharpness given it was their opening game, and perhaps Juve will feel they can take advantage of being in a more advanced stage of pre-season.
Nevertheless, Madrid should be better than they were in their first encounter and with the International Champions Cup seeing precious few clean sheets, we should consider backing a game with goals.
Tips and predictions
At the time of writing this selection has paid out in six of the last nine matches in the International Champions Cup and looks like an intelligent way to back a high scoring game.