It is the first competitive goal for Arsenal scored by the 18-year-old, who has been at Arsenal's Hale End Academy since 2010.
His strike against Qarabag makes him the youngest player to score for Arsenal after Alex Oxlade-Chamberlain's goal against Olympiakos (aged 18 years and 43 days) in September 2011.
18 - Emile Smith-Rowe (18y 67d) is the youngest player to score for Arsenal in a competitive game since Alex Oxlade-Chamberlain against Olympiakos in September 2011 (18y 43d). Blossom. pic.twitter.com/gT8VT8g1wd— OptaJoe (@OptaJoe) October 4, 2018
Smith Rowe's strike was the second Arsenal goal scored away in Azerbaijan, following up from Sokratis' opener which also marked his first for the club.
It has been a season to remember for Smith Rowe who has risen through the ranks of the Arsenal Academy, signing his first professional contract with the club this summer as well as travelling with the team to Singapore for the International Champions' Cup.
Smith Rowe hit the ground running immediately and is an emerging young talent, scoring in the 1-1 draw against Atletico Madrid in the ICC and then assisting a goal in the 5-1 victory over Paris Saint-Germain in the same competition.
The youngster then went on to make his Arsenal first-team debut against Vorskla on September 20 in the Europa League, coming on as a second-half substitute for Alex Iwobi.
Matteo Guendouzi rounded up the scoring to make it a 3-0 win over Qarabag, meaning that all three of Arsenal's goalscorers netted their first goal for the North London side in the same fixture.