Tipped to add to his four Ballon d'Or awards this year, Madrid's all-time leading goalscorer has netted six goals in all competitions this term.
"He's a very important player, but they have lots of very good players," Pochettino said via the Mirror.
"The squad they have is amazing and they have a very good manager. They're a fantastic club, but you need contributions from the whole squad to win titles."
"Cristiano is like [Lionel] Messi, they have a huge impact on their team. He's one of the best players in the world, it's clear," Pochettino added.
"It's difficult to say anything new about these players — like [Diego] Maradona — as they are just special.
"They can change games and make their teams better. We're not just playing Real Madrid, we're playing the best player in the world."
Tottenham and Madrid are level on six points, having both won their opening two Group H fixtures.