The first leg of the last 16 tie takes place next Wednesday and as such it remains to be seen how they approach Saturday's league game against Real Sociedad.
Los Blancos will want to go into the European showdown off the back of a good result, yet will also not want to risk too much ahead of such a key game.
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Zinedine Zidane has practically a fully fit squad to chose from, although his team selection could be conditioned by the PSG game on Wednesday.
La Real midfielder Adnan Januzaj will miss the trip to the capital, as will full-back long-term absentee Carlos Martinez.
Difficult time for Los Blancos
Zidane's men have been surprisingly vulnerable at home this season, winning just nine of the 18 games they have contested at the Bernabeu.
The European champions have also kept just one clean sheet in their last eight matches, and while Real Sociedad have not been in great form they can usually be relied upon to score - their matches average 3.68 goals per game.
Tips and predictions
Real Madrid to win and both teams to score is offered at evens (2.00). This bet has paid out in six of La Real's last seven visits to the Bernabeu, where the Basques tend to score but have not won in 14 years.