Portugal's World Cup frustration has seen them fail to get past the last-16 stage in four of their last five appearances in the competition.
Despite clinching a European title in 2016, they remain behind their continental rivals on the world stage, with Italy, Spain, Germany and France all having won the World Cup since 2000.
Fernando Santos' squad boasts enough quality to challenge any international side but the looming of Cristiano Ronaldo's probable final World Cup appearance in Qatar adds some unwanted extra pressure.
Ronaldo's ongoing stand-off with Manchester United has disrupted his build up to the tournament, with Santos left hoping he can continue to play a talismanic role for Portugal.
Portugal World Cup odds to win
After continually falling short in their previous World Cup appearances, Portugal are not on the list of those marked as the leading candidates to lift the famous trophy in Qatar by the bookmakers, and Santos will be hoping to use that underdog status to his advantage.
However, Group H represents arguably the most even group in the competition, with Portugal up against Ghana, Uruguay and South Korea.
With this in mind, Ned’s rates Portugal chances of clinching World Cup glory in Qatar as a $15 chance.
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Portugal World Cup fixtures
Group H will be the final group to get started in Qatar, with Portugal opening their campaign against Ghana on November 24 in Doha.
That clash is followed by a showdown with old foes Uruguay in Lusail on November 28, before they complete the group stages against South Korea, on December 2 in Al Rayyan.
Each group-stage contest represents a World Cup reunion, with Portugal having faced all three sides in previous tournaments.
Hosts South Korea pulled off a huge shock to knock Portugal out of the 2002 World Cup group stages, while Ronaldo's late goal secured a 2-1 group-stage win over Ghana in 2014.
However, they have real unfinished business against Uruguay, after Edinson Cavani's double dumped Portugal out of the 2018 World Cup at the Round of 16.
Portugal route to World Cup final
Group H could be very difficult for Portugal to navigate their way out of, with Uruguay reaching the last three knockout stages, and Ghana making the knockout stages twice since 2006.
A group-stage exit would be a disaster for Portugal but they will need to be on guard within a strong group.
Round of 16
If Portugal can win Group H, they will face the runners up of Group G, which is most likely to be one of Serbia or Switzerland.
Second place would put them on an almost-certain collision course with Brazil, assuming Tite's side top Group G.
Quarterfinals
First or second place in Group H will have a major impact on Portugal's potential path through the knockout stages in Qatar.
If they get through to the last-16 as Group H winners, the Group F winners will be their most likely opponents in the quarterfinals, with Belgium and Croatia fancied in that group.
Second place in Group H could mean Brazil in the last 16, followed by Spain or Germany in the last eight, if either of those sides win Group E.
Semifinals
If Portugal can break past their previous struggles in the last 16/quarterfinals, top spot in the group could pair them against England or France in the last four.
A second-place finish in Group H could mean Lionel Messi's Argentina in the semis.
Final
Portugal's group-stage finish will have an impact all the way through to a potential final, with first place linking them with Brazil and Argentina and second place more towards England and France.