Last year’s finalists Orlando Pirates will visit Free State Stars, while record-holders Kaizer Chiefs will have a slightly easier task when they visit second division side Acornbush United.
Acornbush stunned Cape Town City in the Last 32, and Amakhosi will have to be wary of the threat the Eastern Cape outfit poses.
Mamelodi Sundowns will be at home against fellow Premier Soccer League side Golden Arrows.
Bidvest Wits will make a short trip to Brakpan to face Jomo Cosmos.
Chippa United v Polokwane City
Kwa-Dukuza United v SuperSport United
Bloemfontein Celtic v Mbombela United
Free State Stars v Orlando Pirates
Jomo Cosmos v Bidvest Wits
Baroka v Platinum Stars
Mamelodi Sundowns v Golden Arrows
Acornbush United v Kaizer Chiefs