The win see the Zambian club advance to the group stage of the tournament with a 5-2 aggregate margin having registered a 2-2 draw against Enugu Rangers in their first leg meeting.
On Saturday, John Ching’andu scored twice in the first-half; the first goal being in the 25th minute and the second coming 14 minutes later.
Former Tusker forward Jesse Were then came to make it 3-0 in the 62nd minute to seal the sweet victory.
Zesco United: Jacob Banda, Daut Musekwa, Fackson Kapumbu, Ben Adama Banh, David Owino Odhiambo , Kondwani Mtonga, Dave Daka, Anthony Akumu, Jesse Jackson Were, Idris Mbombo, John Chingandu.
Subs: Lameck Nyangu, Mwape Mwelwa, Marcel Kalonda, Maybin Kalengo, Lazarous Kambole, Patrick Kongolo, Bernard Mapili.