After knocking Napoli off top spot with an impressive away victory last time out, Juventus will be hoping to underline their title credentials even further when current leaders Inter visit Turin on Saturday.
However, Luciano Spalletti's men are the only unbeaten side left in the league after 15 fixtures, and are on offer at 4/1 (5.00) to tighten their grip on pole position with a big win in this one.
Just one of the last seven encounters between these sides has resulted in a draw, but you can get odds of 11/4 (3.75) on them cancelling each other out on this occasion.
With the Scudetto race looking tighter than it has in years, victory at the San Paolo served as a major statement for Massimiliano Allegri's team.
Having started the campaign in far less dominant fashion than the form that has won them six consecutive titles, a solid 1-0 away win over an impressive Napoli side offered proof that they are returning to their formidable best.
Indeed, Tuesday's crucial 2-0 Champions League win away to Olympiakos means Allegri's side has now kept four consecutive clean sheets - a run that includes games against Barcelona as well as free-scoring Napoli.
While this resolute defensive form should serve them well against the Nerazzurri, a breakthrough at the other end of the pitch is far from a given against Serie A's joint-best defence.
All in all, odds of 9/10 (1.90) seem generous on under 2.5 goals being scored in another heavyweight clash involving Juventus - a bet that would have paid out in each of Inter's last three league visits to this ground.
Odds correct at the time of writing. Please gamble responsibly.