Another defeat of Kotoko this weekend could trigger the dismissal of coach Samuel Paa Kwasi Fabin, who is under intense pressure to improve the club’s standing on the log.
The Porcupine Warriors, like arch-rivals Hearts of Oak, are enduring a torrid time in the championship this season.
With Kotoko having won four games, drawn two and lost on five occasions, Sunday's home match may well be the final straw for Fabin should he fail to steer the Porcupine Warriors to victory over seventh-placed Bechem United.
Hearts boss Henry Wellington, on the other hand, has a short respite as his side will not be in action this weekend owing to the postponement of their game with Aduana Stars, who have a Caf Confederation Cup clash with ASEC Mimosas of Cote d'Ivoire on Sunday.
Elsewhere, leaders Ashanti Gold are eyeing their seventh victory of the campaign in their away encounter with fifth-spotted Elmina Sharks. The game is the only matchday 12 fixture slated for Saturday.
Tying Ashgold on points, Dreams FC could assume the top spot should they snatch an unlikely win at Medeama, who sit four points below.
Third-placed Karela United play as guests of fourth-from-bottom Liberty Professionals at the Carl Reindorf Park.
At Techiman, new boys Eleven Wonders will face off against Ebusua Dwarfs. Whereas the debutants hold the 12th spot, the Crabs occupy the 15th position.
Wafa have a date with 2015-16 champions All Stars in the final game of Sunday at Sogakope. The Academy Boys lie fourth on the table as the Northern Blues sit rock bottom.