Having been forced to settle for second place at the European Championships on home soil two years ago, Didier Deschamps' men will be determined to go one better on this occasion.
France are amongst the favourites to take the title this summer and it is little surprise that Les Bleus are as short as 1/4 (1.25) with bet365 to open their campaign with victory here.
The Socceroos stuttered on the road to Russia, eventually scraping past Syria in an Asian qualification play-off before beating Honduras over two legs in the Intercontinental play-off round.
The two youngest players at the World Cup - Daniel Arzani of Australia and Kylian Mbappe of France - could go head-to-head in this fixture.
Both players scored in their respective nations' final friendly fixtures before the tournament, although it is Mbappe who looks more likely to start.
Arzani could find himself on the substitutes' bench alongside former Everton star Tim Cahill, with Tomi Juric expected to be given the nod in attack for the Socceroos.
Socceroos set to struggle?
France have been in free-scoring form in recent months, scoring at least two goals in 10 of their last 11 wins.
Australia have managed just one clean sheet in their last 10 competitive matches and bet365's 8/1 (9.0) quote for the Socceroos to shut out Les Bleus is indicative of the challenge Van Marwijk's side face.
Australia conceded four goals in a friendly fixture against Norway back in March and the Socceroos could find themselves comprehensively outclassed in what looks to be a fiercely competitive group.
Les Bleus will be determined to lay down a significant marker here and bet365's 5/4 (2.25) quote for Deschamps' side to score more than two goals could represent real value ahead of Saturday's showdown.
Odds correct at the time of writing. Please gamble responsibly.