Leeds have turned to Thomas Christiansen to build on Garry Monk's work at Elland Road last season, with a host of new faces arriving in West Yorkshire.
Bolton, meanwhile, are back in the second tier after Phil Parkinson led them to promotion in his first season in charge, though they start the campaign as one of the favourites for relegation.
|Game||Bolton Wanderers vs Leeds United|
|Date||Sunday, August 6|
TV CHANNEL & LIVE STREAM
In the UK, the match will be available to watch live on television on Sky Sports Football and by stream via Sky Go and NOW TV.
|UK TV channel||Online stream|
|Sky Sports Football, Sky Sports Main Event||Sky Go, NOW TV|
If you live outside of the UK, you will be able to stream all of your club's non-televised matches live through the Football League's new iFollow service this season.
A subscription to the platform costs £110 for the 2017-18 campaign and will grant you full access to up to 46 games. For more details, see the EFL's website.
SQUAD & TEAM NEWS
|Position||Bolton Wanderers players|
|Goalkeepers||Ben Alnwick, Mark Howard, Jake Turner|
|Defenders||Mark Little, Andrew Taylor, Dorian Dervite, Mark Beevers, Derik Osede Prieto, Stephen Darby, David Wheater, Reece Burke, Antonee Robinson|
|Midfielders||Josh Vela, Chris Taylor, Jem Karacan, Josh Cullen, Darren Pratley, Filipe Morais, Alex Perry, Jack Earing|
|Forwards||Adam Le Fondre, Gary Madine, Adam Armstrong, Sammy Ameobi, Will Buckley, Aaron Wilbraham|
Phil Parkinson has been busy in the transfer market over the past week, adding four new faces to his squad ahead of the opening day.
However, the likelihood is that the quartet will, at best, start from the bench, with the XI that played in the club's final pre-season friendly against Stoke City set to kick-off the campaign.
Possible line-up: Howard; Dervite, Wheater, Beevers; Darby, Pratley, Karacan, Vela, A. Taylor; Madine, Le Fondre.
|Position||Leeds United players|
|Goalkeepers||Robert Green, Felix Wiedwald, Bailey Peacock-Farrell|
|Defenders||Luke Ayling, Liam Cooper, Pontus Jansson, Matthew Pennington, Gaetano Berardi|
|Midfielders||Eunan O'Kane, Kalvin Phillips, Ronaldo Vieira, Liam Brdicutt, Mateusz Klich, Vurnon Anita, Pablo Hernandez, Samuel Saiz|
|Forwards||Chris Wood, Marcus Antonsson, Souleymane Doukara, Caleb Ekuban, Kemar Roofe, Stuart Dallas, Hadi Sacko, Ezgjan Alioski|
Leeds are without key centre-back Pontus Jansson due to suspension, so Everton loanee Matthew Pennington is likely to partner Liam Cooper in defence.
Elsewhere there will likely be competitive debuts for Felix Wiedwald, Samuel Saiz and Ezgjan Alioski while Ronaldo Vieira faces a battle to be fit to start at the Macron Stadium.
Possible line-up: Wiedwald; Ayling, Cooper, Pennington, Berardi; O'Kane, Vieira; Roofe, Saiz, Alioski; Wood.
BETTING & MATCH ODDS
Leeds are the slight favourites with dabblebet pricing them at 6/4 to take all three points while Bolton can be backed at 15/8 with the draw 9/4.
Having finished as the Championship's top scorer last season with 27 goals, Leeds striker Chris Wood is priced at 11/8 to find the net again, with his odds of opening the scoring at 17/4.
After an encouraging campaign under Garry Monk that saw them finish just outside the play-off positions in 2016-17, there is a feeling that Leeds are having to start all over again under new coach Thomas Chritiansen.
The former Barcelona striker has never managed in England, with much of his success coming in Cyprus, and there is a sense among supporters at Elland Road that they are somewhat stepping into the unknown.
Of the seven new signings Christiansen has brought in this summer, only Vurnon Anita and Matthew Pennington have previous experience of English football, and as such it has proven difficult to predict quite how the upcoming campaign will pan out for Leeds.
Bolton, meanwhile, secured promotion at the first time of asking under Phil Parkinson last season, and are hopeful that they can establish themselves again in the second tier of English football.
Parkinson has been busy this summer and has looked to add players who performed so well for him during his time at Bradford City to his squad, with the likes of Stephen Darby, Reece Burke and Josh Cullen all arriving during the close season.
Given their performances last season, hosting Leeds on the opening day could prove tough for the Lancashire side, but Parkinson will be hopeful of making a winning start to life back in the Championship.